DEVELOPMENTS IN EXPLORING FUNGAL SECONDARY METABOLITES AS ANTIVIRAL COMPOUNDS AND ADVANCES IN HIV-1 INHIBITOR SCREENING ASSAYS

Developments in Exploring Fungal Secondary Metabolites as Antiviral Compounds and Advances in HIV-1 Inhibitor Screening Assays

The emergence of drug-resistant Human Immunodeficiency Virus-1 strains against anti-HIV therapies in the clinical pipeline, and the persistence of HIV in cellular reservoirs remains a significant concern.Therefore, there is a continuous need to discover and develop new, safer, and effective drugs targeting novel sites to combat HIV-1.The Hockey Sti

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Extracellular galectin-3 in tumor progression and metastasis

Galectin-3, the only chimera galectin found in vertebrates, is one of the best-studied galectins.It is expressed in several cell types and is involved in a broad range of physiological and pathological processes, such as cell adhesion, cell activation and chemoattraction, cell cycle, apoptosis and cell growth and differentiation.However, this molec

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